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How sleep and gut flora can affect your life

Cómo el sueño y la flora intestinal pueden afectar tu vida

It’s probably happened to you. It's late, hours go by, heartburn or reflux bothers you, you’re tossing and turning in bed, and you can’t sleep. As a result, the next day, you wake up exhausted, cranky, and with an upset stomach. Truth is, skipping those recommended 7 to 9 hours of sleep can affect you more than you think. Find out how altering your circadian rhythm and its relationship with the intestinal flora impacts your overall well-being. 

  • Having a bad night and not getting enough sleep affects your central nervous system because the brain is exhausted and, therefore, cannot perform its functions, such as retaining new information and maintaining concentration, and can even negatively affect your emotional state. (1)
  • A lack of sleep can harm the immune system as it prevents it from developing its defenses and producing antibodies. By not resting, your body may not be able to defend itself against invaders, and it may even take longer to recover from an illness.
  • Sleep also affects the processes that keep the heart and blood vessels healthy, including blood sugar levels, blood pressure, and inflammation. It also plays a vital role in the body’s ability to heal and repair blood vessels and the heart.
  • This may surprise you, but lack of sleep is another risk factor for being overweight and obese, along with poor diet and lack of exercise. Sleep affects the levels of two hormones, leptin and ghrelin, which control feelings of hunger and satiety. Leptin is responsible for letting the brain know that you ate enough, and without sleep, the brain reduces leptin and increases ghrelin, which is an appetite stimulant.
  • On the other hand, lack of sleep can impact your intestinal flora and digestive health. While you sleep, the digestive system is busy repairing and rebuilding gut tissues and cultivating good gut bacteria that support digestive processes. When there is poor digestion, acids can rise in the digestive tract during the night, interrupting sleep and causing coughing, snoring, and other discomforts that do not allow you to rest. 
  • The relationship between the brain and the intestinal flora is very close. The brain is what controls sleep or the circadian rhythm, and one of the main neurotransmitters to fulfill this task of unwinding and falling asleep is serotonin. However, it has been discovered that most serotonin is produced in the gastrointestinal tract. It is an endless circle and a complex network in which both parts need to function properly. (2)

These are just a few of the many reasons why having a good night’s rest and healthy gut flora is crucial. If you are deprived of the right to proper sleep, we have a new Santo Remedio that can help you restore your biological clock, rest better, and wake up feeling completely refreshed without drowsiness. Plus, it supports the intestinal flora to reduce digestive problems that interrupt your sleep.

Introducing Buenas Noches, an innovative supplement that has powerful natural ingredients to restore sleep and digestive health that, as you can see, go hand in hand.

  • It contains Zylaria®, a proprietary botanical blend that can help calm the central nervous system, allowing the body and mind to relax and fall asleep faster. It does this in different ways: first, by increasing the neurotransmitter called GABA, which helps relax and improve the quality of sleep. Secondly, by helping you fall asleep more quickly, and thirdly, allowing that sleep to be of better quality and last longer.
  • It also includes a blend of herbs and ingredients such as L-theanine, chamomile, lemon balm, and passionflower, along with 5 mg of melatonin that also helps promote sleep.
  • Finally, it contains the patented ingredient DE111® (Bacillus subtilis), a powerful strain of probiotics that can survive passage through the gastrointestinal tract to help restore the balance of positive bacteria in the intestinal microflora, supporting the digestive system to reduce problems such as heartburn or reflux.

As you can see, sleep and ensuring that your intestinal flora is in balance are not luxuries, but necessities for your overall health and emotional well-being to keep you focused on your priorities. We are here to help you achieve it!

Your Santo Remedio team.



  1. Eleonora Tobaldini a b, Giorgio Costantino a, Monica Solbiati a, Chiara Cogliati c, Tomas Kara d e, Lino Nobili f, Nicola Montano a b g, Neurosci Biobehav Rev. 2017 Mar;74(Pt B):321-329. doi: 10.1016/j.neubiorev.2016.07.004. Epub 2016 Jul 7., Pages 321-329 Sleep, sleep deprivation, autonomic nervous system and cardiovascular diseases
  2. Jeremy Appleton, ND*, Integr Med (Encinitas). 2018 Aug; 17(4): 28–32. PMCID: PMC6469458 The Gut-Brain Axis: Influence of Microbiota on Mood and Mental Health
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